Monthly Archives: July 2016

Combination Antidepressant Therapy May Not Improve Odds of Remission Among Chronically Depressed

A combination of two antidepressants may not be any more effective in treating chronic major depression than a single antidepressant, according to an NIMH-funded study published online ahead of print May 2, 2011, in theAmerican Journal of Psychiatry. Background When … Continue reading

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Thinking Globally to Improve Mental Health

Mental health experts are calling for a greater world focus on improving access to care and treatment for mental, neurological, and substance use (MNS) disorders, as well as increasing discoveries in research that will enable this goal to be met. … Continue reading

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Switching Antipsychotics May Reduce Metabolic Risks

Patients experiencing cardiovascular or metabolic side effects while taking an antipsychotic medication may fare better if they switch to a different medication provided they are closely monitored, according to an NIMH-funded study. The study was published online ahead of print … Continue reading

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Widely Used Screening Tool Shown to Successfully Predict Suicide Attempts

A widely used suicide screening tool can help determine who is most at risk for suicide by pinpointing the threshold at which a person’s suicidal thinking is severe enough to warrant professional intervention, according to a recent study published online … Continue reading

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Experimental Medication Lifts Depression Symptoms in Bipolar Disorder Within an Hour

People with treatment-resistant bipolar disorder experienced relief from symptoms of depression in as little as 40 minutes after an intravenous dose of the anesthetic medication ketamine in a preliminary study; while the patient group was small, this work adds to … Continue reading

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Ketamine Cousin Rapidly Lifts Depression Without Side Effects

GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the street drug side effects, reported a preclinical study funded by the National Institute of Mental Health (NIMH) that was published last month inNeuropsychopharmacology. Background Major depression affects about … Continue reading

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Light Switches Brain Pathway On-and-Off to Dissect How Anxiety Works

Scientists, for the first time, have switched anxiety on-and-off in active animals by shining light at a brain pathway. Instinctively reclusive mice suddenly began exploring normally forbidding open spaces when a blue laser activated the pathway – and retreated into … Continue reading

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Mood Disorders Predict Later Substance Abuse Problems

Mania symptoms and bipolar disorder II more likely to lead to substance abuse than depression January 9, 2008 • Science Update People with manic symptoms and bipolar disorder type II are at significant risk of later developing an alcohol abuse … Continue reading

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Continued Use of Stimulants for ADHD Likely Does Not Increase Risk for Hypertension, but May Affect Heart Rate

September 7, 2011 • Science Update Source: NIMH Chronic use of stimulant medication to treat attention deficit hyperactivity disorder (ADHD) in children does not appear to increase risk for high blood pressure over the long term, but it may have … Continue reading

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Prescribed stimulant use for ADHD continues to rise steadily

September 28, 2011 • Press Release NIH and AHRQ study finds pace of the rise has slowed in recent years Source: NIMH The prescribed use of stimulant medications to treat attention deficit hyperactivity disorder (ADHD) rose slowly but steadily from … Continue reading

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