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sorry all my computer is acting up I can barely type without my cursor going all over the place as soon as it is fixed I will be back to posting thanks for your patience LOL Jan

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More links to mental health web sites

Links To Mental Health Websites

Following are state and national websites that are known to be reputable and to have good up to date information. Many of these sites have mental health related fact sheets that may be downloaded free of charge.

National Alliance for the Mentally Ill
www.nami.org

National Institute of Mental Health
www.nimh.nih.gov

National Mental Health Association
www.nmha.org

Mental Health Association in Michigan
www.mha-mi.org

American Academy of Child and Adolescent Psychiatry
www.aacap.org

American Psychiatric Association
www.psych.org

American Psychological Association
www.apa.org

SAMHSA National Mental Health Information Center
Substance Abuse and Mental Health Services Administration
www.mentalhealth.samhsa.org

Anxiety Disorders Association of America
www.adaa.org

Recovery Michigan
www.recovery-michigan.org

Suicide Prevention Resource Center
www.sprc.org

National Suicide Prevention Lifeline
www.suicidepreventionlifeline.org

Stop A Suicide
www.StopASuicide.org

American Association of Suicidology
www.suicidology.org

WebMD
www.webmd.com

Autism Society of America
www.autism-society.org

Children and Adults with Attention Deficit Disorder (CHADD)
www.chadd.org

Parents with a Mental Illness
www.parentingwell.org

Depression Bipolar Support Alliance
www.DBSAlliance.org

Bipolar Children
www.bpchildren.com

National Schizophrenia Foundation
www.nsfoundation.org

Prevent Child Abuse America
www.preventchildabuse.org

Postpartum Support International (PSI)
www.postpartum.net

Michigan Assistive Technology Resource (MATR)
www.cenmi.org/matr/

Michigan Assistive Technology Exchange
www.atxchange.org

National Dissemination Center for Children with Disabilities (NICHCY)
www.nichcy.org

Recovery Michigan
www.recovery-michigan.org

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Mental Health Links helpful

Mental Health Links
The following links are listed to provide you with additional online mental health care information and counseling resources. The links are not endorsed or controlled by The Center for Therapy & Counseling Services, and we are not responsible for the content provided on these sites.

Addiction and Recovery
Alcoholics Anonymous
Alcoholics Anonymous Recovery Resources
Center for On-Line Addiction
Habit Smart
SAMHSA’s Substance Abuse/Addiction
SAMHSA’s Treatment and Recovery
Web of Addictions

Anxiety Disorders
Answers to Your Questions About Panic Disorder
National Center for PTSD
Obsessive Compulsive Information Center

Associations & Institutes
American Academy of Child & Adolescent Psychiatry
American Association for Marriage and Family Therapy
American Counseling Association
American Psychiatric Association
American Psychological Association
American Psychological Society
Canadian Mental Health Association
Center for Mental Health Services
National Institute of Mental Health
National Mental Health Association
Substance Abuse and Mental Health Services Administration

Attention-Deficit Hyperactivity Disorder
ADDA – Attention Deficit Disorder Association
Attention-Deficit Hyperactivity Disorder, NIMH
Born to Explore: The Other Side of ADD/ADHD

Child Abuse and Domestic Violence
Childhelp USA®
SAMHSA’s Children and Families
SAMHSA’s Protection and Advocacy
Questions and Answers about Memories of Childhood Abuse
The National Domestic Violence Hotline Website
Women, Violence and Trauma

Chronic Fatigue
Chronic Fatigue Syndrome

Depression
Bipolar Disorder News – Pendulum.org
Depression and How Therapy Can Help
Depression Screening
Depression Test, Symptoms of Depression, Signs of Depression

Developmental Disorders
Asperger’s Disorder
NeuroWeb
Pervasive Developmental Disorders

Diagnosis
DSM-IV-TR: Diagnoses and Criteria

Dissociation and Traumatic Stress
Sidran Foundation Home Page

Eating Disorders
American Dietetic Association
Something Fishy

Journals & Magazines
ADHD Report
Anxiety, Stress and Coping
Autism
Childhood
Contemporary Hypnosis
Dementia
Depression and Anxiety
Dreaming
Drug and Alcohol Review
Dyslexia
Early Child Development and Care
Eating Disorders
Educational Assessment
Journal of Gambling Studies
Journal of Happiness Studies
Journal of Mental Health and Aging
Journal of Sex & Marital Therapy
Journal of Sport and Exercise Psychology
Journal of Substance Abuse Treatment
Language and Cognitive Processes
Loss, Grief & Care
Mental Retardation and Developmental Disabilities
Metaphor and Symbol
Neuropsychological Rehabilitation
Parenting
Personal Relationships
Personality and Individual Differences
Psychiatric Bulletin
Psychology of Men & Masculinity
Psychology Today
Stress and Health
Studies in Gender and Sexuality
Substance Abuse
Suicide and Life-Threatening Behavior
Trauma, Violence & Abuse

Medications and Health Supplements
Drug Interactions, Alternative, MotherNature
Drug Interactions, DIRECT
Medical Dictionary
Medications, FDA
Medication, Internet Mental Health
Medications, PDR
Medline, Comparison
Multivitamins
SAMHSA’s Psychiatry and Psychology

Mental Health Care General Links
CounsellingResource.com
GoodTherapy.org
Internet Mental Health
Let’s Talk Facts, APA
Mental Health Counselor Resources, About.com
Mental Help Net
Mental Illnesses/Disorders
PsychCentral.com
University of Michigan Health Topics A to Z
Web Sites You Can Trust, Medical Library Association

Personality Disorders
Mental Help Net – Personality Disorders
Personality Disorders – Focus Adolescent Counselor Services

Suicide Awareness and Hotlines
SAMHSA’s Suicide
Suicide Awareness Voices of Education
Suicide: Read This First

Additional Mental Health Care & Counseling Resources
Disaster/Trauma
HIV/AIDS
Interpretation of Dreams
Keirsey (Myers-Briggs) Temperament Sorter
Signs of Menopause, Symptoms of Menopause


Note:
Not responsible for the content, claims or representations of the listed sites.

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Substance Abuse and Mental Health

Substance Abuse and Co-Occurring Disorders

When you have both a substance abuse problem and a mental health issue such as depression, bipolar disorder, or anxiety, it is called a co-occurring disorder or dual diagnosis. Dealing with substance abuse, alcoholism, or drug addiction is never easy, and it’s even more difficult when you’re also struggling with mental health problems, but there are treatments that can help. With proper treatment, support, and self-help strategies, you can overcome a dual diagnosis and reclaim your life.

Understanding the link between substance abuse and mental health

In a dual diagnosis, both the mental health issue and the drug or alcohol addiction have their own unique symptoms that may get in the way of your ability to function, handle life’s difficulties, and relate to others. To make the situation more complicated, the co-occurring disorders also affect each other and interact. When a mental health problem goes untreated, the substance abuse problem usually gets worse as well. And when alcohol or drug abuse increases, mental health problems usually increase too.

What comes first: Substance abuse or the mental health problem?

Addiction is common in people with mental health problems. But although substance abuse and mental health disorders like depression and anxiety are closely linked, one does not directly cause the other.

Alcohol or drugs are often used to self-medicate the symptoms of depression or anxiety. Unfortunately, substance abuse causes side effects and in the long run worsens the very symptoms they initially numbed or relieved.

Alcohol and drug abuse can increase underlying risk for mental disorders. Mental disorders are caused by a complex interplay of genetics, the environment, and other outside factors. If you are at risk for a mental disorder, drug or alcohol abuse may push you over the edge.

Alcohol and drug abuse can make symptoms of a mental health problem worse. Substance abuse may sharply increase symptoms of mental illness or trigger new symptoms. Alcohol and drug abuse also interact with medications such as antidepressants, anti-anxiety pills, and mood stabilizers, making them less effective.

Addiction is common in people with mental health problems

According to reports published in the Journal of the American Medical Association:

  • Roughly 50 percent of individuals with severe mental disorders are affected by substance abuse.
  • 37 percent of alcohol abusers and 53 percent of drug abusers also have at least one serious mental illness.
  • Of all people diagnosed as mentally ill, 29 percent abuse either alcohol or drugs.

Source: National Alliance on Mental Illness

Recognizing co-occurring disorders or dual diagnosis

It can be difficult to diagnose a substance abuse problem and a co-occurring mental health disorder such as depression, anxiety, or bipolar disorder. It takes time to tease out what might be a mental disorder and what might be a drug or alcohol problem.

Complicating the issue is denial. Denial is common in substance abuse. It’s hard to admit how dependent you are on alcohol or drugs or how much they affect your life. Denial frequently occurs in mental disorders as well. The symptoms of depression or anxiety can be frightening, so you may ignore them and hope they go away. Or you may be ashamed or afraid of being viewed as weak if you admit the problem.

Admitting you have a dual diagnosis or co-occurring disorders

Just remember: substance abuse problems and mental health issues don’t get better when they’re ignored. In fact, they are likely to get much worse. You don’t have to feel this way. Admitting you have a problem is the first step towards conquering your demons and enjoying life again.

Consider family history. If people in your family have grappled with either a mental disorder such as depression or alcohol abuse or drug addiction, you have a higher risk of developing these problems yourself.

Consider your sensitivity to alcohol or drugs. Are you highly sensitive to the effects of alcohol or drugs? Have you noticed a relationship between your substance use and your mental health? For example, do you get depressed when you drink?

Look at symptoms when you’re sober. While some depression or anxiety is normal after you’ve stopped drinking or doing drugs, if the symptoms persist after you’ve achieved sobriety, you may be dealing with a mental health problem.

Review your treatment history. Have you been treated before for either your addiction or your mental health problem? Did the substance abuse treatment fail because of complications from your mental health issue or vice versa?

Signs and symptoms of substance abuse

If you’re wondering whether you have a substance abuse problem, the following questions may help. The more “yes” answers, the more likely your drinking or drug use is a problem.

  1. Have you ever felt you should cut down on your drinking or drug use?
  2. Have you tried to cut back, but couldn’t?
  3. Do you ever lie about how much or how often you drink or use drugs?
  4. Have your friends or family members expressed concern about your alcohol or drug use?
  5. Do you ever felt bad, guilty, or ashamed about your drinking or drug use?
  6. On more than one occasion, have you done or said something while drunk or high that you later regretted?
  7. Have you ever blacked out from drinking or drug use?
  8. Has your alcohol or drug use caused problems in your relationships?
  9. Has you alcohol or drug use gotten you into trouble at work or with the law?

Signs and symptoms of common co-occurring disorders

The mental health problems that most commonly co-occur with substance abuse are depression, anxiety disorders, and bipolar disorder.

Common signs and symptoms of depression
  • Feelings of helplessness and hopelessness
  • Loss of interest in daily activities
  • Inability to experience pleasure
  • Appetite or weight changes
  • Sleep changes
  • Loss of energy
  • Strong feelings of worthlessness or guilt
  • Concentration problems
  • Anger, physical pain, and reckless behavior (especially in men)
Common signs and symptoms of mania in bipolar disorder
  • Feelings of euphoria or extreme irritability
  • Unrealistic, grandiose beliefs
  • Decreased need for sleep
  • Increased energy
  • Rapid speech and racing thoughts
  • Impaired judgment and impulsivity
  • Hyperactivity
  • Anger or rage
Common signs and symptoms of anxiety
  • Excessive tension and worry
  • Feeling restless or jumpy
  • Irritability or feeling “on edge”
  • Racing heart or shortness of breath
  • Nausea, trembling, or dizziness
  • Muscle tension, headaches
  • Trouble concentrating
  • Insomnia

Treatment for substance abuse and mental health problems

The best treatment for co-occurring disorders is an integrated approach, where both the substance abuse problem and the mental disorder are treated simultaneously.

Recovery depends on treating both the addiction and the mental health problem

Whether your mental health or substance abuse problem came first, recovery depends on treating both disorders.

There is hope. Recovering from co-occurring disorders takes time, commitment, and courage. It may take months or even years but people with substance abuse and mental health problems can and do get better.

Combined treatment is best. Your best chance of recovery is through integrated treatment for both the substance abuse problem and the mental health problem. This means getting combined mental health and addiction treatment from the same treatment provider or team.

Relapses are part of the recovery process. Don’t get too discouraged if you relapse. Slips and setbacks happen, but, with hard work, most people can recover from their relapses and move on with recovery.

Peer support can help. You may benefit from joining a self-help support group like Alcoholics Anonymous or Narcotics Anonymous. They give you a chance to lean on others who know what you’re going through and learn from their experiences.

How to find the right program for co-occurring disorders

As with a substance abuse program, make sure that the program is appropriately licensed and accredited, the treatment methods are backed by research, and there is an aftercare program to prevent relapse. Additionally, you should make sure that the program has experience with your particular mental health issue. Some programs, for example, may have experience treating depression or anxiety, but not schizophrenia or bipolar disorder.

There are a variety of approaches that treatment programs may take, but there are some basics of effective treatment that you should look for:

  • Treatment addresses both the substance abuse problem and your mental health problem.
  • You share in the decision-making process and are actively involved in setting goals and developing strategies for change.
  • Treatment includes basic education about your disorder and related problems.
  • You are taught healthy coping skills and strategies to minimize substance abuse, cope with upset, and strengthen your relationships.

Treatment for dual diagnosis or co-occurring disorders

  • Helping you think about the role that alcohol and other drugs play in your life. This should be done confidentially, without any negative consequences. People feel free to discuss these issues when the discussion is confidential, nonjudgmental, and not tied to legal consequences.
  • Offering you a chance to learn more about alcohol and drugs, to learn about how they interact with mental illnesses and with medications, and to discuss your own use of alcohol and drugs.
  • Helping you become involved with supported employment and other services that may help your process of recovery.
  • Helping you identify and develop your own recovery goals. If you decide that your use of alcohol or drugs may be a problem, a counselor trained in integrated dual diagnosis treatment can help you identify and develop your own recovery goals. This process includes learning about steps toward recovery from both illnesses.
  • Providing special counseling specifically designed for people with dual diagnosis. This can be done individually, with a group of peers, with your family, or with a combination of these.

Source: SAMHSA

Treatment programs for veterans with co-occurring disorders

Veterans deal with additional challenges when it comes to co-occurring disorders. The pressures of deployment or combat can exacerbate underlying mental disorders, and substance abuse is a common way of coping with unpleasant feelings or memories. Often, these problems take a while to show up after a vet returns home, and may be initially mistaken for readjustment. Untreated co-occurring disorders can lead to major problems at home and work and in your daily life, so it’s important to seek help.

Veterans often benefit from treatment and support from specialized programs that address the unique stresses veterans face.

Group support for substance abuse and co-occurring disorders

As with other addictions, groups are very helpful, not only in maintaining sobriety, but also as a safe place to get support and discuss challenges. Sometimes treatment programs for co-occurring disorders provide groups that continue to meet on an aftercare basis. Your doctor or treatment provider may also be able to refer you to a group for people with co-occurring disorders.

While it’s often best to join a group that addresses both substance abuse and your mental health disorder, twelve-step groups for substance abuse can also be helpful—plus they’re more common, so you’re likely to find one in your area. These free programs, facilitated by peers, use group support and a set of guided principles—the twelve steps to obtain and maintain sobriety.

Just make sure your group is accepting of the idea of co-occurring disorders and psychiatric medication. Some people in these groups, although well meaning, may mistake taking psychiatric medication as another form of addiction. You want a place to feel safe, not pressured.

Self-help for substance abuse and co-occurring disorders

Getting sober is only the beginning. Your continued recovery depends on continuing mental health treatment, learning healthier coping strategies, and making better decisions when dealing with life’s challenges.

Recovery tip 1: Recognize and manage overwhelming stress and emotions

Learn how to manage stress. Stress is inevitable, so it’s important to have healthy coping skills so you can deal with stress without turning to alcohol or drugs. Stress management skills go a long way towards preventing relapse and keeping your symptoms at bay.

Know your triggers and have an action plan. If you’re coping with a mental disorder as well, it’s especially important to know signs that your illness is flaring up. Common causes include stressful events, big life changes, or unhealthy sleeping or eating. At these times, having a plan in place is essential to preventing drug relapse. Who will you talk to? What do you need to do?

Recovery tip 2: Stay connected

Get therapy or stay involved in a support group. Your chances of staying sober improve if you are participating in a social support group like Alcoholics Anonymous or Narcotics Anonymous or if you are getting therapy.

Follow doctor’s orders. Once you are sober and you feel better, you might think you no longer need medication or treatment. But arbitrarily stopping medication or treatment is a common reason for relapse in people with co-occurring disorders. Always talk with your doctor before making any changes to your medication or treatment routine.

Recovery tip 3: Make healthy lifestyle changes

Practice relaxation techniques. When practiced regularly, relaxation techniques such as mindfulness meditation, progressive muscle relaxation, and deep breathing can reduce symptoms of stress, anxiety, and depression, and increase feelings of relaxation and emotional well-being.

Adopt healthy eating habits. Start the day right with breakfast, and continue with frequent small meals throughout the day. Going too long without eating leads to low blood sugar, which can make you feel more stressed or anxious.

Exercise regularly. Exercise is a natural way to bust stress, relieve anxiety, and improve your mood and outlook. To achieve the maximum benefit, aim for at least 30 minutes of aerobic exercise on most days.

Get enough sleep. A lack of sleep can exacerbate stress, anxiety, and depression, so try to get 7 to 9 hours of quality sleep a night.

Helping a loved one with a substance abuse and mental health problem

Helping a loved one with both a substance abuse and a mental health problem can be a roller coaster. Resistance to treatment is common and the road to recovery can be long.

The best way to help someone is to accept what you can and cannot do. You cannot force someone to remain sober, nor can you make someone take their medication or keep appointments. What you can do is make positive choices for yourself, encourage your loved one to get help, and offer your support while making sure you don’t lose yourself in the process.

Seek support. Dealing with a loved one’s dual diagnosis of mental illness and substance abuse can be painful and isolating. Make sure you’re getting the emotional support you need to cope. Talk to someone you trust about what you’re going through. It can also help to get your own therapy or join a support group.

Set boundaries. Be realistic about the amount of care you’re able to provide without feeling overwhelmed and resentful. Set limits on disruptive behaviors, and stick to them. Letting the co-occurring disorders take over your life isn’t healthy for you or your loved one.

Educate yourself. Learn all you can about your loved one’s mental health problem, as well as substance abuse treatment and recovery. The more you understand what your loved one is going through, the better able you’ll be to support recovery.

Be patient. Recovering from a dual diagnosis doesn’t happen overnight. Recovery is an ongoing process that can take months or years, and relapse is common. Ongoing support for both you and your loved one is crucial as you work toward recovery.

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Management of Bipolar Disorder

Am Fam Physician. 2000 Sep 15;62(6):1343-1353

ACF  This article exemplifies the AAFP 2000 Annual Clinical Focus on mental health.

Bipolar disorder most commonly is diagnosed in persons between 18 and 24 years of age. The clinical presentations of this disorder are broad and include mania, hypomania and psychosis. Frequently associated comorbid conditions include substance abuse and anxiety disorders. Patients with acute mania must be evaluated urgently. Effective mood stabilizers include lithium, valproic acid and carbamazepine. A comprehensive management program, including collaboration between the patient’s family physician and psychiatrist, should be implemented to optimize medical care.

Bipolar disorder is characterized by variations in mood, from elation and/or irritability to depression. This disorder can cause major disruptions in family, social and occupational life. Bipolar I disorder is defined as episodes of full mania alternating with episodes of major depression. Patients with mania often exhibit disregard for danger and engage in high-risk behaviors such as promiscuous sexual activity, increased spending, violence, substance abuse and driving while intoxicated.

Bipolar II disorder is characterized by recurrent episodes of major depression and hypomania. Hypomania is manifested by an elevated and expansive mood. The behaviors characteristic of hypomania are similar to those of mania but without gross lapses of impulse and judgment. Hypomania does not cause impairment of function and may actually enhance function in the short term.

Bipolar I disorder is typically diagnosed when patients are in their early 20s. Manic symptoms can rapidly escalate over a period of days and frequently follow psychosocial stressors. Some patients initially seek treatment for depression. Other patients may appear irritable, disorganized or psychotic. Differentiating true mania from mania resulting from secondary causes can be challenging (Table 1).1,2

TABLE 1
Causes of Secondary Mania

The rightsholder did not grant rights to reproduce this item in electronic media. For the missing item, see the original print version of this publication.

Bipolar II disorder typically is brought to medical attention when the patient is depressed. A careful history will usually illuminate the diagnosis. Some depressed patients exhibit hypomania when given antidepressants.3 This variation is sometimes referred to as bipolar III disorder. The criteria for major depressive episode and manic episode, as described in the Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV), are summarized in Table 2.4

View/Print Table

TABLE 2

Criteria for Major Depressive Episode and Manic Episode

Major depressive episode

Five or more of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure.

1. Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g., appears tearful). Note: In children and adolescents, can be irritable mood.

2. Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others)

3. Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day. Note: In children, consider failure to make expected weight gains.

4. Insomnia or hypersomnia nearly every day

5. Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down)

6. Fatigue or loss of energy nearly every day

7. Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick)

8. Diminished ability to think or concentrate, or indeciseveness, nearly every day (either by subjective account or as observed by others)

9. Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide

Manic episode

A. A distinct period of abnormally and persistently elevated, expansive, or irritable mood, lasting at least 1 week (or any duration if hospitalization is necessary)

B. During the period of mood disturbance, three (or more) of the following symptoms have persisted (four if the mood is only irritable) and have been present to a significant degree:

1. Inflated self-esteem or grandiosity

2. Decreased need for sleep (e.g., feels rested after only 3 hours of sleep)

3. More talkative than usual or pressure to keep talking

4. Flight of ideas or subjective experience that thoughts are racing

5. Distractibility (i.e., attention too easily drawn to unimportant or irrelevant external stimuli)

6. Increase in goal-directed activity (either socially, at work or school, or sexually) or psychomotor agitation

7. Excessive involvement in pleasurable activities that have a high potential for painful consequences (e.g., engaging in unrestrained buying sprees, sexual indiscretions, or foolish business investments)


Reprinted with permission from American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, D.C.: American Psychiatric Association, 1994:327,332. Copyright 1994.

Epidemiology

The lifetime prevalence of bipolar disorder is 1 percent, which compares to a lifetime prevalence of 6 percent for unipolar depression.5 The prevalence of bipolar disorder does not differ in males and females.6 The disorder affects persons of all ages. The epidemiologic catchment area study revealed the highest prevalence in the 18-to-24-year age group.7 In some patients, however, bipolar disorder does not become manifest until patients are older. One study reported new-onset bipolar disorder in patients older than 60 years.8

The incidence of bipolar disorder is increased in first-degree relatives of persons with the disorder, as is the incidence of other mood disorders.9 One study revealed a 13 percent risk of bipolar disorder among offspring of persons with the disorder.10 The risk of unipolar depression was 15 percent, and the risk of schizoaffective disorder was 1 percent.10 The mode of inheritance remains unclear, and no algorithm exists to predict the risk of bipolar disorder.11 Because of the familial association, genetic counseling should be offered to patients and their families as part of comprehensive educational and supportive approaches.

Clinical Presentations

Patients with symptoms of a mood disorder often do not meet the full criteria for bipolar disorder. Many patients with bipolar disorder are diagnosed as having depression. If agitation is prominent, hypomanic symptoms may be misunderstood as representing an anxiety state. Accurate diagnosis of bipolar disorder requires obtaining a comprehensive psychiatric history.

CHILDREN

Hyperactivity is the most common behavioral manifestation of mania in children.12 Manic children may exhibit irritability or temper tantrums.13 The differential psychiatric diagnoses include attention-deficit/hyperactivity disorder, conduct disorder and schizophrenia.14

ADOLESCENTS

Manic symptoms in adolescents are similar to those in adults. Florid psychosis can be a presentation of bipolar disorder in adolescents. Included in the differential diagnosis of mania in adolescents are substance abuse and schizophrenia, which may be challenging to distinguish from bipolar disorder. The normal risk-taking behavior in some adolescents must be distinguished from the reckless nature of manic symptoms.

DURING PREGNANCY

The course of bipolar disorder during pregnancy is variable. Management requires sustained collaboration between the patient’s family physician and her psychiatrist. A patient with bipolar disorder should be encouraged to plan pregnancy so that the dosage of her psychiatric medication can be slowly tapered. The risk of relapse is increased with abrupt discontinuation.15

Relapse during pregnancy must be treated aggressively with mood stabilizers. The patient should be admitted to the hospital. If lithium therapy is required, the patient should be counseled regarding the increased risk of cardiovascular malformations in fetuses exposed to lithium. Breast-feeding during lithium therapy is discouraged because lithium is excreted in breast milk.16

During the postpartum period, worsening of affective symptoms may occur, including rapid cycling, which is sometimes refractory to drug therapy.17 Women who have worsening of symptoms postpartum may have an increased risk of recurrence.

Comorbid Conditions

Studies of primary care patients with major depressive disorders have demonstrated a tendency toward certain comorbid conditions. In one study,18 more than 42 percent of patients meeting the criteria for a major depressive disorder (including bipolar disorder) had lifetime histories of substance abuse. In another study,19 the frequency of substance abuse was 39 percent in adolescents who had symptoms of bipolar disorder. Another study20 revealed a high prevalence of moderate to severe anxiety disorders in association with bipolar disorder, as well as a high prevalence of psychosocial morbidity.

While many patients with bipolar disorder show gradual improvement in the first several years after diagnosis, a substantial subgroup experiences poor adjustment in one or more areas of functioning.21 In a study of psychiatric patients who were evaluated 30 to 40 years after the index hospitalization for mania, 24 percent of the sample was considered to be occupationally incapacitated.22

Treatment

URGENT AND EMERGENT

If a patient with symptoms of acute mania presents to the office, a psychiatrist should be consulted, and the patient should be evaluated urgently. The family physician must know the legal requirements in the community for transferring a patient with acute mania from the office to the hospital. Often, police must be involved. It is inappropriate to expect family members to transport the patient from the office to the hospital, because family members may not appreciate the irrationality of manic thinking and the unpredictability of manic behavior.

The family physician and psychiatrist have the responsibility to inform, educate and support family members in terms of the possible need for the family to petition the court for the patient’s admission to a psychiatric unit. It is important to recognize, and to try to allay, the guilt and regret family members often feel in these circumstances.

Patients with newly diagnosed bipolar disorder require a medical evaluation along with a psychiatric evaluation. Table 323 lists the recommended laboratory tests for patients evaluated on an inpatient or an outpatient basis. Computed tomography or magnetic resonance imaging and electroencephalography are second-line options in the evaluation of treatment-resistant patients. These studies are not routinely required without a specific clinical reason. Similarly, the need for electrocardiography in patients younger than 40 years rests with the clinician’s judgment.

If necessary, and if the patient has been in good general health, mood stabilizers, as well as other drugs used in the treatment of bipolar disorder, can be started before the test results are available. If the need to begin treatment is urgent, medication can be given even before laboratory specimens are obtained.

View/Print Table

TABLE 3

Laboratory Evaluation of Patients Presenting with Bipolar Disorder

Inpatient

Complete physical examination

Serum levels of lithium, valproic acid (Depakene), carbamazepine (Tegretol) and selected tricyclic antidepressants (if relevant)

Thyroid function tests

Complete blood count and general chemistry screening

Urinalysis if lithium therapy is initiated

Electrocardiography in patients older than 40 years

Urine toxicology for substance abuse

Pregnancy test (if relevant)

Outpatient

Complete physical examination

Serum levels of lithium, valproic acid, carbamazepine and selected tricyclic antidepressants (if relevant)

Thyroid function tests

Complete blood count and general chemistry screening

Urinalysis if lithium therapy is initiated

Pregnancy test (if relevant)

Second-line tests: urine toxicology for substance abuse and electrocardiography in patients older than 40 years


Adapted with permission from Steering Committee. Treatment of bipolar disorder. The Expert Consensus Guideline Series. J Clin Psychiatry 1996;57(suppl 12A):3–88.

COLLABORATIVE ONGOING CARE

Given the chronic nature of bipolar disorder and its impact on the entire family, it is important for the patient’s family physician and psychiatrist to develop an effective and collaborative relationship. Informed collaboration depends on an agreed method of communication in a frequency that meets the needs of each physician.24 A Canadian model brings psychiatrists and counselors into family practice offices for shared care.25

At the onset of bipolar disorder, the family physician might seek psychiatric consultation for differential diagnosis and treatment recommendations. Often, the psychiatrist assumes responsibility for initial management until the patient’s clinical pattern is determined. During follow-up, both physicians should monitor the patient for signs of psychosis, mood swings, violence and self-harmful behaviors. As the patient’s illness stabilizes and management becomes routine, the physicians can renegotiate, with each other and with the patient, responsibility for ongoing care.

When the patient’s condition has become stable, the psychiatrist may not need to see the patient as often, although the frequency of follow-up psychiatric visits depends on the course of the illness, the patient’s adherence to treatment, medication requirements, the need for ongoing psychotherapy and patterns of care in a particular geographic area. It is important for the patient’s family physician and psychiatrist to coordinate medication prescriptions and follow-up laboratory tests such as determination of serum drug levels. In addition, counseling and family therapy are important components of management and may be rendered by the family physician, psychiatrist and/or psychologist.

MEDICATION

Recommendations for drug therapy in patients with bipolar disorder are summarized in Table 4.23

Medication is the key to stabilizing bipolar disorder. Initial treatment of mania consists of lithium or valproic acid (Depakene). If the patient is psychotic, a neuroleptic medication is also given. Long-acting benzodiazepines may be used for treating agitation. However, in patients with a substance-abuse history, benzodiazepines should be used with caution because of the addictive potential of these agents.

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TABLE 4

Recommendations for Drug Therapy in Patients with Bipolar Disorder

Considerations for prescribing mood stabilizers

Lithium: For classic, euphoric mania; for mixed manic episode; when a mood stabilizer alone is used to treat depression; when the mood stabilizer must be given in a single evening dose; in patients with liver disease, excessive alcohol use or cocaine use; and in patients older than 65 years

Valproic acid (Depakene): For classic, euphoric mania; for mixed manic episode; for mania with rapid cycling; for long-term maintenance therapy in patients who do not tolerate lithium because of the “flat” feeling lithium causes; in patients with structural central nervous system disease, renal disease and cocaine use; and in patients older than 65 years

Carbamazepine (Tegretol): For mixed manic episode; for mania with rapid cycling; in patients with structural central nervous system disease or renal disease

An antipsychotic agent

High- or medium-potency antipsychotic agents are used as adjunctive treatment for mania with psychosis or psychotic depression.

A benzodiazepine

Sleep and sedation in mania or hypomania; insomnia in depression

The combination of a mood stabilizer, an antidepressant and an antipsychotic

Psychotic depression

The combination of a mood stabilizer and an antidepressant

Nonpsychotic depression

A mood stabilizer alone

Milder depression in bipolar I disorder

Bupropion (Wellbutrin)

Bipolar depression

Patient with high risk of manic switch or rapid cycling

A selective serotonin reuptake inhibitor

Bipolar depression


Adapted with permission from Steering Committee. Treatment of bipolar disorder. The Expert Consensus Guideline Series. J Clin Psychiatry 1996;57(suppl 12A):3–88.

When the patient with bipolar disorder becomes depressed, a selective serotonin reuptake inhibitor (SSRI) or bupropion (Wellbutrin) is recommended.26 The use of tricyclic antidepressants should be avoided because of the possibility of inducing rapid cycling of symptoms.

Drug interactions are an important consideration when prescribing lithium (Table 5),27  valproic acid (Table 6)27  and a selective serotonin reuptake inhibitor (Table 7).27  Information about starting and maintenance dosages for lithium, valproic acid and carbamazepine (Tegretol) is summarized in Table 8.23

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TABLE 5

Drug Interactions with Lithium

DRUG EFFECT ON LITHIUM LEVEL MANAGEMENT

Thiazide diuretics

Increased lithium level

Avoid this combination or reduce dosage; monitor lithium level

Loop diuretics

Increased or decreased lithium level

Avoid this combination or alter either dosage as needed; monitor lithium level

Potassium-sparing diuretics

Decreased lithium level

Monitor lithium level and adjust dosage

Nonsteroidal anti-inflammatory drugs

Increased lithium level

Use lower dosage of lithium; consider aspirin or sulindac

Angiotensin-converting enzyme inhibitors

Increased lithium level; toxicity reported

Use lower dosage of lithium; monitor lithium level closely

Calcium channel blockers

Increased or decreased lithium level

Monitor lithium level closely


Adapted with permission from DeVane CL, Nemeroff CB. 1998 Guide to psychotropic drug interactions. Primary Psychiatry 1998;5:36–75.

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TABLE 6

Drug Interactions with Valproic Acid (Depakene)

DRUG INTERACTION MANAGEMENT

Phenobarbital

Increased phenobarbital level

Reduce dosage

Magnesium- and aluminum- containing antacids

Increased valproic acid level

Monitor valproic acid level; reduce dosage

Carbamazepine (Tegretol)

Decreased valproic acid level; possible increased carbamazepine level

Monitor valproic acid level; adjust dosage

Aspirin and naproxen (Naprosyn)

Increased valproic acid level

Avoid salicylates or other drugs bound to plasma albumin

Clonazepam (Klonopin)

Increased sedation

Use with caution


Adapted with permission from DeVane CL, Nemeroff CB. 1998 Guide to psychotropic drug interactions. Primary Psychiatry 1998;5:36–75.

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TABLE 7

Drug Interactions with Selective Serotonin Reuptake Inhibitors

DRUG INTERACTION MANAGEMENT

Alprazolam (Xanax)

Increased alprazolam levels

Monitor; reduce dosage

TCAs

Increased TCA level

Monitor TCA level

Warfarin (Coumadin)

Increased warfarin level with fluvoxamine (Luvox)

Monitor prothrombin time (INR); reduce fluvoxamine dosage

MAOIs

Serotonin syndrome

Combination of MAOI and SSRI is contraindicated

Clozapine (Clozaril)

Increased clozapine level with fluvoxamine

Monitor clozapine level

l-Tryptophan

Serotonin syndrome

Combination of L-tryptophan and SSRI is contraindicated

Phenytoin (Dilantin)

Possible phenytoin toxicity

Monitor phenytoin level

Carbamazepine (Tegretol)

Increased carbamazepine level with fluvoxamine and fluoxetine (Prozac)

Monitor carbamazpine level

Tolbutamide

Possible increased hypoglycemia

Monitor blood glucose level

Theophylline

Increased theophylline level with fluvoxamine

Monitor theophylline level

Cimetidine (Tagamet)

Increased SSRI levels

Monitor clinically

Type Ic antiarrhythmics

Increased antiarrhythmic level with fluoxetine, paroxetine (Paxil) and sertraline (Zoloft)

Monitor antiarrhythmic drug levels

Beta-adrenergic blockers

Increased beta-blocker level and enhanced effects

Use lower beta-blocker dosage

Codeine

Inhibited metabolism from fluoxetine, paroxetine and sertraline

Use different SSRI

St. John’s wort

Serotonin syndrome

Stop St. John’s wort before beginning SSRI therapy


SSRI = selective serotonin reuptake inhibitor; TCA = tricyclic antidepressant; INR = International Normalized Ratio; MAOI = monoamine oxidase inhibitor.

Adapted with permission from DeVane CL, Nemeroff CB. 1998 Guide to psychotropic drug interactions. Primary Psychiatry 1998;5:36–75.

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TABLE 8

Starting and Maintenance Dosages of Lithium, Valproic Acid and Carbamazepine and Common Side Effects

INITIAL DOSING STRATEGY* MAINTENANCE DOSAGE† COMMON SIDE EFFECTS‡ COST (GENERIC)§

Lithium

900 mg per day; increase by 300 to 600 mg every 2 to 3 days as tolerated

900 to 1,800 mg per day; 1,200 mg may be given as a single bedtime dose if tolerated; otherwise, prescribe twice-daily dosingTherapeutic blood level: 0.8 to 1.5 mEq per L

Thirst, polyuria, cognitive complaints, tremor,∥ weight gain, sedation, diarrhea, nausea (watch for dehydration, which can lead to toxicity), hypothyroidism (monitor TSH; give levothyroxine [Synthroid] if TSH is elevated)

One 300-mg capsule: $0.19 (0.06 to 0.10)

Valproic acid (Depakene)

20 mg per kg per day for mania; adjust dosage in 3 to 5 daysAn alternative is 500 to 750 mg daily; increase by 30 to 50 percent every 2 to 3 days as tolerated

1,000 to 3,000 mg per day. Lower dosages may be used in hypomania. Sometimes it is appropriate to give as a single bedtime dose; otherwise, prescribe twice-daily dosingTherapeutic blood level: 50 to 125 μg per mL

Tremor, ∥ sedation, diarrhea, nausea (use divalproex [Depakote]; give histamine H2-receptor blocker such as ranitidine [Zantac], 150 mg daily); weight gain, hair loss, mild elevation on liver function tests

One 250-mg capsule: $1.24

Carbamazepine (Tegretol)

200 to 400 per day; increase by 200 mg daily every 2 to 4 days

400 to 1,200 mg daily; in an occasional patient, it is appropriate to give a single bedtime dose; otherwise, prescribe twice-daily dosingTherapeutic blood level: 4 to 12 μg per mL; not well established

Headache, nystagmus, ataxia, sedation, rash, leukopenia (do not combine with clozapine [Clorazil]), mild elevation on liver function tests. Carbamazepine is associated with frequent drug–drug interactions related to induction of cytochrome P450 liver enzymes, resulting in lower drug levels of many other medications.

One 200-mg tablet: $0.44 (0.29 to 0.33)


TSH = thyroid-stimulating hormone.

*—When initiating therapy, consider lower dosages in patients with hypomania and in medically ill or elderly patients.

—Consolidate doses to twice daily or once daily at bedtime if tolerated and efficacious.

—Many of the side effects are dose related. Tolerance can be enhanced by tailoring the dosage to each patient’s tolerance and response.

§ —Estimated cost to the pharmacist for one tablet or capsule based on average wholesale prices rounded to the nearest dollar in Red book. Montvale, N.J.: Medical Economics Data, 1999. Cost to the patient will be higher, depending on prescription filling fee.

—Tremor may be relieved with a beta-adrenergic blocker such as atenolol (Tenormin), in a dosage of 50 mg daily.

Adapted with permission from Steering Committee. Treatment of bipolar disorder. The Expert Consensus Guideline Series. J Clin Psychiatry 1996;57(suppl 12A):3–88.

MONITORING ISSUES

Treatment with mood stabilizers requires periodic laboratory tests to monitor the patient’s response to the drug (Table 9).23 In addition, preventive care includes surveillance for possible comorbidities. Screening for substance abuse and other mental health problems should be conducted routinely. If prodromal symptoms of depression or mania are noted, interventions may include more frequent office visits, crisis telephone calls and intensive outpatient programs.23 It is important that patients regulate their sleep. Insufficient and irregular hours of sleep often precipitate mood disturbance.

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TABLE 9

Recommended Laboratory Tests for Monitoring Response to Lithium, Valproic Acid and Carbamazepine

LITHIUM VALPROIC ACID (DEPAKENE) CARBAMAZEPINE (TEGRETOL)

First two months of therapy

Serum level every 1 to 2 weeks*†

Serum level every 1 to 2 weeks*CBC and liver function tests monthly

Serum level every 1 to 2 weeks*CBC and liver function tests monthly

Long-term therapy

Serum level every 3 to 6 months*†Thyroid function tests yearly (total T4, T4 uptake and TSH)†Renal function every 6 to 12 months (serum urea nitrogen, creatinine and electrolytes); 24-hour urine for volume and GFR only if specifically indicated, not routinely

Serum level every 3 to 6 months*†CBC and liver function tests every 6 to 12 months

Serum level every 3 to 6 months*CBC and liver function tests every 6 months


CBC = complete blood count; T4 = thyroxine; TSH = thyroid-stimulating hormone; GFR = glomerular filtration rate.

*—Serum levels of mood stabilizers should be obtained whenever the dosage or clinical situation changes.

—Tests are strongly recommended by the committee that formulated the guidelines for treatment of bipolar disorder.

Adapted with permission from Steering Committee. Treatment of bipolar disorder. The Expert Consensus Guideline Series. J Clin Psychiatry 1996;57(suppl 12A):3–88.

Family and Psychosocial Issues

Significant issues for the patient and family members include the stigma that is frequently associated with mental illness and the need for support and education. Because patients with bipolar disorder lose judgment early in the course of the illness and often engage in high-risk behavior, family members may be interacting with the legal system, the police and the health care system simultaneously. Guilt, anger, grief and ambivalence are frequent feelings among family members as they cope with the difficulties.

Family members must be educated about possible relapses, what to look for and how to handle different situations. The recklessness that accompanies mania can have devastating consequences—including sexually transmitted diseases, financial ruin, traumatic injuries and accidents. Risk-taking causes significant distress to patients and families, and such behavior is a problem for which family physicians, psychiatrists and mental health professionals can intervene with appropriate medical, preventive, educational and social strategies (Table 10).23 Initial intervention includes education for the patient and family, including informational pamphlets, videos and involvement in support and patient advocacy groups.

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TABLE 10

Psychosocial Issues to Address in the Acute and Maintenance Phases of Bipolar Disorder

Acute phase

Monitor suicidality, mood, substance use, sleep patterns and medication compliance.

Educate patient and family members about features and biologic nature of the illness and the importance of compliance with therapy.

Encourage telephone contact and optimism regarding recovery. Set limits on impulsive behavior in patients with mania. Consider interpersonal or cognitive therapy for patients with depression. Hold family meetings to discuss issues.

Maintenance phase

Inquire about suicidality, mood, medication compliance, life events, substance use, sleep and activity.

Educate patient and family members about use of medication, warning signs of relapse, management of stress, sleep hygiene, eating and exercising regularly, limited caffeine and alcohol intake and management of work and leisure activities.

Long-range issues may include marital problems, employment and financial problems, peer relationships and modification of personality traits.


Adapted with permission from Steering Committee. Treatment of bipolar disorder. The Expert Consensus Guideline Series. J Clin Psychiatry 1996;57(suppl 12A):3–88.

Patients who are manic or depressed may attempt suicide or homicide. The risk is increased in patients who are psychotic and have severe depressive symptoms concurrent with mania.28 The lifetime suicide risk is 15 percent in patients with bipolar disorder; patients at highest risk are young men in an early phase of illness who have made previous suicide attempts or who abuse alcohol.29Family members must learn the warning signs of suicide and must be able to distinguish between the signs of mania and those of depression.

Substance use should be discouraged. Even modest social drinking can lead to mood disturbance. In addition, substances such as alcohol can interact with medications, disinhibit patients and contribute to risky behaviors.

Guns should be removed from the house. Easy access to firearms can supply a ready means of suicide or accidental injury in a patient with impaired insight and judgment.

If the patient or family has concerns about sexually transmitted diseases, testing and counseling can be offered and preventive strategies explained and encouraged.

Legal intervention may be required in patients who exhibit violent behavior. Spouses should be informed of their legal rights, given crisis intervention information and access to safe houses.

If a patient is out of control in spending money, several avenues should be explored. Patients and family members may need referral to social services and/or to legal counsel. Precautions might include putting the house in the spouse’s name, limiting credit lines, creating trust funds and using financial planning services. Support groups are useful, as is family therapy.

Final Comment

Bipolar disorder can be well managed by family physicians in concert with psychiatrists. The consequences of the patient’s behavior on the patient’s life as well as the lives of family members must be explored. The family physician has a significant contribution to make in terms of education, support and follow-up. Both family physicians and psychiatrists have opportunities to intervene and help these patients and their families.

The Authors

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KIM S. GRISWOLD, M.D., M.P.H., is assistant professor of family medicine and psychiatry in the Department of Family Medicine at the State University of New York (SUNY) at Buffalo School of Medicine and Biomedical Sciences. She received a master’s degree in public health from Yale University, New Haven, Conn., and completed a faculty development fellowship in primary care at Michigan State University College of Human Medicine, East Lansing. After graduating from the SUNY–Buffalo School of Medicine and Biomedical Sciences, she completed a family practice residency at Buffalo (N.Y.) General Hospital.

REFERENCES

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1. Krauthammer C, Klerman GL. Secondary mania. Arch Gen Psychiatry. 1978;35:1333–9.

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Social Phobia Positive Affirmations

Present Tense Affirmations
I am relaxed in public
I enjoy parties
I embrace social situations
I thrive in crowds
I am confident
I look forward to parties
I am outgoing and friendly
I have an inner calm in crowds
I am socially adept
I enjoy being social

 

Future Tense Affirmations
I will have fun at parties
I will enjoy talking with others
I will seek out social situations
I am becoming more comfortable in groups
I will relax in groups
I will enjoy meeting new people
I am becoming more confident around others
I will become more outgoing
I will thrive in crowds
I will stay calm around others

 

Natural Affirmations
My personality is outgoing
Others enjoy meeting me
Others invite me to parties often
Meeting new people is fun
Engaging with others comes naturally to me
Confidence is one of my traits
Attending parties is fun
Being around others is relaxing
Crowds are fun to be in
Social situations are fun
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Spiritual Quotation

By: Nancy Azara

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Anger Management Positive Affirmations

Present Tense Affirmations
I am in control
I am calm, focused, and relaxed
I remain calm even when under intense stress
I have the power to regulate my emotions
I always stay calm in difficult or frustrating situations
I am able to diffuse my anger and channel it in a more productive way
I control my anger by expressing myself in a firm yet positive manner
I always speak my mind rather than let frustrations build up
I am able to calm myself down and detach from anger
I allow myself to acknowledge angry feelings without losing control

 

Future Tense Affirmations
I will control myself
I am starting to effectively manage my anger
Staying relaxed is becoming easier
I will remain calm and centered in frustrating situations
Managing my anger will create a better life for myself and my loved ones
I am transforming into someone who confronts problems constructively
Each day it is becoming easier to diffuse my anger
I am gaining more and more control over my emotions
I will become a positive person whom others can turn to without fear
Anger management is changing my life for the better

 

Natural Affirmations
Being calm, relaxed, and in control is normal for me
Controlling my anger comes naturally to me
I find it easy to calm myself down and relax
It is important that I learn to manage my anger
I believe I can break free from anger and live a better life
Diffusing anger is easy for me
Thinking positively in tough situations is just something I do naturally
I owe it to myself to manage my anger
Managing anger will help to repair and strengthen my bond to friends and family
I am a naturally calm, easy going, and positive person
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Bipolar II Disorder

What Is Bipolar II Disorder?

Bipolar II disorder (pronounced “bipolar two”) is a form of mental illness. Bipolar II is similar to bipolar I disorder, with moods cycling between high and low over time.

However, in bipolar II disorder, the “up” moods never reach full-blown mania. The less-intense elevated moods in bipolar II disorder are called hypomanic episodes, or hypomania.

A person affected by bipolar II disorder has had at least one hypomanic episode in his or her life. Most people with bipolar II disorder suffer more often from episodes of depression. This is where the term “manic depression” comes from.

In between episodes of hypomania and depression, many people with bipolar II disorder typically live normal lives.

A Visual Guide to Understanding Bipolar Disorder

Who Is at Risk for Bipolar II Disorder?

Virtually anyone can develop bipolar II disorder. About 2.5% of the U.S. population suffers from some form of bipolar disorder – nearly 6 million people.

Most people are in their teens or early 20s when symptoms of bipolar disorder first start. Nearly everyone with bipolar II disorder develops it before age 50. People with an immediate family member who has bipolar are at higher risk.

What Are the Symptoms of Bipolar II Disorder?

During a hypomanic episode, elevated mood can manifest itself as either euphoria (feeling “high”) or as irritability.

Symptoms during hypomanic episodes include:

  • Flying suddenly from one idea to the next
  • Having exaggerated self confidence
  • Rapid, “pressured” (uninterruptable) and loud speech
  • Increased energy, with hyperactivity and a decreased need for sleep

People experiencing hypomanic episodes are often quite pleasant to be around. They can often seem like the “life of the party” — making jokes, taking an intense interest in other people and activities, and infecting others with their positive mood.

What’s so bad about that, you might ask? Hypomania can also lead to erratic and unhealthy behavior. Hypomanic episodes can sometimes progress onward to full manias that affect a person’s ability to function (bipolar I disorder). In mania, people might spend money they don’t have, seek out sex with people they normally wouldn’t, and engage in other impulsive or risky behaviors with the potential for dangerous consequences.

The vast majority of people with bipolar II disorder experience more time with depressive than hypomanic symptoms. Depressions can occur soon after hypomania subsides, or much later. Some people cycle back and forth between hypomania and depression, while others have long periods of normal mood in between episodes.

Untreated, an episode of hypomania can last anywhere from a few days to several months. Most commonly, symptoms continue for a few weeks to a few months.

Depressive episodes in bipolar II disorder are similar to “regular” clinical depression, with depressed mood, loss of pleasure, low energy and activity, feelings of guilt or worthlessness, and thoughts of suicide. Depressive symptoms of bipolar disorder can last weeks, months, or rarely years.

What Are the Treatments for Bipolar II Disorder?

Hypomania often masquerades as happiness and relentless optimism. When hypomania is not causing unhealthy behavior, it often may go unnoticed and therefore remain untreated. This is in contrast to full mania, which by definition causes problems in functioning and requires treatment with medications and possibly hospitalizations.

People with bipolar II disorder can benefit from preventive drugs that level out moods over the long term. These prevent the negative consequences of hypomania, and also help to prevent episodes of depression.

Mood Stabilizers

Lithium: This simple metal in pill form is highly effective at controlling mood swings (particularly highs) in bipolar disorder. Lithium has been used for more than 60 years to treat bipolar disorder. Lithium can take weeks to work fully, making it better for long-term treatment than for acute hypomanic episodes. Blood levels of lithium and other laboratory tests (such as kidney and thyroid functioning) must be monitored periodically to avoid side effects.

Carbamazepine (Tegretol): This antiseizure drug has been used to treat mania since the 1970s. Its possible value for treating bipolar depression, or preventing future highs and lows, is less well-established. Blood tests to monitor liver functioning and white blood cell counts also are periodically necessary.

Lamotrigine (Lamictal): This drug is approved by the FDA for the maintenance treatment of adults with bipolar disorder. It has been found to help delay bouts of mood episodes of depression, mania, hypomania (a milder form of mania), and mixed episodes in people being treated with standard therapy. It is especially helpful in preventing lows.

Valproate (Depakote): This antiseizure drug also works to level out moods. It has a more rapid onset of action than lithium, and it can also be used “off label” for prevention of highs and lows.

Some other antiseizure medications, such as gabapentin (Neurontin), oxcarbazapine (Trileptal), and topiramate (Topamax) are also sometimes prescribed as “experimental” (less-proven) treatments for mood symptoms or associated features in people with bipolar disorder.

Antipsychotics

By definition, hypomanic episodes do not involve psychosis and do not interfere with functioning. Antipsychotic drugs, such as aripiprazole(Abilify), cariprazine (Vraylar), quetiapine (Seroquel), asenapine(Saphris), olanzapine (Zyprexa), risperidone (Risperdal), and ziprasidone (Geodon) and others, are nevertheless sometimes used in hypomania and some (notably, Seroquel) are used for depression in bipolar II disorder.

Benzodiazepines

This class of drugs includes alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan) and is commonly referred to as minor tranquilizers. They are used for short-term control of acute symptoms associated with hypomania such as insomnia or agitation.

Antidepressants

Seroquel and Seroquel XR are the only medications FDA-approved specifically for bipolar II depression. Common antidepressants such as fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft) are also sometimes used in bipolar II depression, and are thought to be less likely to cause or worsen hypomania than is the case in bipolar I disorder. Other medicines sometimes used to treat bipolar II depression include mood stabilizers such as lithium or Depakote, and occasionally Lamictal(although the proven value of Lamictal in bipolar disorder is stronger for preventing relapses than treating acute episodes of bipolar depression). Psychotherapy, such as cognitive-behavioral therapy, may also help.

Because bipolar II disorder typically involves recurrent episodes, continuous and ongoing treatment with medicines is often recommended for relapse prevention.

Can Bipolar II Disorder Be Prevented?

The causes of bipolar disorder are not well understood. It’s not known if bipolar II disorder can be prevented entirely.

It is possible to reduce the risk for developing future episodes of hypomania or depression once bipolar disorder has developed. Regular therapy sessions with a psychologist or social worker, in combination with medication, can help efforts to stabilize mood, leading to fewer hospitalizations and feeling better overall. Psychotherapy can help people better recognize the warning signs of a developing relapse before it takes hold, and can also help to ensure that prescribed medicines are being taken properly.

How Is Bipolar II Disorder Different From Other Types of Bipolar Disorder?

People with bipolar I disorder experience full mania — a severe, abnormally elevated mood with erratic behavior. Manic symptoms lead to serious disruptions in life, causing legal or major personal problems.

In bipolar II disorder, the symptoms of elevated mood never reach full-blown mania. Hypomania in bipolar II is a milder form of mood elevation. However, the depressive episodes of bipolar II disorder are often longer-lasting and may be even more severe than in bipolar I disorder. Therefore, bipolar II disorder is not simply a “milder” overall form of bipolar disorder.

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Bipolar I Disorder

What Is Bipolar I Disorder?

Bipolar I disorder (pronounced “bipolar one” and also known as manic-depressive disorder or manic depression) is a form of mental illness. A person affected by bipolar I disorder has had at least one manic episode in his or her life. A manic episode is a period of abnormally elevated mood and high energy, accompanied by abnormal behavior that disrupts life.

Most people with bipolar I disorder also suffer from episodes of depression. Often, there is a pattern of cycling between mania and depression. This is where the term “manic depression” comes from. In between episodes of mania and depression, many people with bipolar I disorder can live normal lives.

Understanding Bipolar Disorder

Who Is at Risk for Bipolar I Disorder?

Virtually anyone can develop bipolar I disorder. About 2.5% of the U.S. population suffers from bipolar disorder — almost 6 million people.

Most people are in their teens or early 20s when symptoms of bipolar disorder first appear. Nearly everyone with bipolar I disorder develops it before age 50. People with an immediate family member who has bipolar are at higher risk.

What Are the Symptoms of Bipolar I Disorder?

During a manic episode in someone with bipolar disorder, elevated mood can manifest itself as either euphoria (feeling “high”) or as irritability.

Abnormal behavior during manic episodes includes:

  • Flying suddenly from one idea to the next
  • Rapid, “pressured” (uninterruptable), and loud speech
  • Increased energy, with hyperactivity and a decreased need for sleep
  • Inflated self-image
  • Excessive spending
  • Hypersexuality
  • Substance abuse

People in manic episodes may spend money far beyond their means, have sex with people they wouldn’t otherwise, or pursue grandiose, unrealistic plans. In severe manic episodes, a person loses touch with reality. They may become delusional and behave bizarrely.

Untreated, an episode of mania can last anywhere from a few days to several months. Most commonly, symptoms continue for a few weeks to a few months. Depression may follow shortly after, or not appear for weeks or months.

Many people with bipolar I disorder experience long periods without symptoms in between episodes. A minority has rapid-cycling symptoms of mania and depression, in which they may have distinct periods of mania or depression four or more times within a year. People can also have mood episodes with “mixed features,” in which manic and depressive symptoms occur simultaneously, or may alternate from one pole to the other within the same day.

Depressive episodes in bipolar disorder are similar to “regular” clinical depression, with depressed mood, loss of pleasure, low energy and activity, feelings of guilt or worthlessness, and thoughts of suicide. Depressive symptoms of bipolar disorder can last weeks or months, but rarely longer than one year.

What Are the Treatments for Bipolar I Disorder?

Manic episodes in bipolar I disorder require treatment with drugs, such as mood stabilizers and antipsychotics, and sometimes sedative-hypnotics which include benzodiazepines such as clonazepam (Klonopin) or lorazepam (Ativan).

Mood Stabilizers

Lithium: This simple metal in pill form is especially effective at controlling mania that involves classical euphoria rather than mixtures of mania and depression simultaneously. Lithium has been used for more than 60 years to treat bipolar disorder. Lithium can take weeks to work fully, making it better for maintenance treatment than for sudden manic episodes. Bloodlevels of lithium as well as tests to measure kidney and thyroidfunctioning must be monitored to avoid side effects.

Valporate (Depakote): This antiseizure medication also works to level out moods. It has a more rapid onset of action, often making it more effective for an acute episode of mania than lithium. It is also often used “off label” for prevention of new episodes. As a mood stabilizer that can be used by a “loading dose” method — beginning at a very high dose — valporate allows the possibility of significant improvement in mood as early as four to five days.

Some other antiseizure drugs, notably carbamazepine (Tegretol) and lamotrigine (Lamictal), can have value in treating or preventing manias or depressions. Other antiseizure medicines that are less well-established but still sometimes used experimentally for the treatment of bipolar disorder, include gabapentin (Neurontin), oxcarbazapine (Trileptal), and topiramate (Topamax).

Antipsychotics

For severe manic episodes, traditional antipsychotics (such as Haldol, Loxapine, or Thorazine) as well as newer antipsychotic drugs — also called atypical antipsychotics — may be necessary. Cariprazine (Vraylar) is a newly approved antipsychotic to treat manic or mixed episodes. Aripiprazole (Abilify),  asenapine (Saphris),  clozapine (Clozaril), olanzapine (Zyprexa), quetiapine  (Seroquel), risperidone (Risperdal), and ziprasidone (Geodon) are often used, and many other drugs are available. The antipsychotic lurasidone (Latuda) is approved for use — either alone or with lithium or valproate (Depakote) — in cases of bipolar I depression.Antipsychotic medicines are also sometimes used for preventive treatment.

Benzodiazepines

This class of drugs includes alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan) and is commonly referred to as minor tranquilizers. They are sometimes used for short-term control of acute symptoms associated with mania such as agitation or insomnia, but they do not treat core mood symptoms such as euphoria or depression.

Antidepressants

Common antidepressants such as fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft) have not been shown to be as effective for treating depression in bipolar disorder as in unipolar depression. In a small percentage of people, they can also set off or worsen a manic episode in a person with bipolar disorder. For these reasons, the first-line treatments for depression in bipolar disorder involve medicines that have been shown to have antidepressant properties but also no known risk for causing or worsening mania. The three FDA-approved treatments for bipolar depression are lurasidone (Latuda), olanzapinefluoxetine(Symbyax) combination, quetiapine (Seroquel) or quetiapine fumarate (Seroquel XR). Other mood-stabilizing treatments that are sometimes recommended for treating acute bipolar depression include lithium, Depakote, and Lamictal (although none of these later three medicines is FDA-approved specifically for bipolar depression). If these fail, after a few weeks a traditional antidepressant or other medicine may sometimes be added. Psychotherapy, such as cognitive-behavioral therapy, may also help.

People with bipolar I disorder (mania or depression) have a high risk for recurrences and usually are advised to take medicines on a continuous basis for prevention.

Electroconvulsive Therapy (ECT)

Despite its scary reputation, electroconvulsive therapy (ECT) is an effective treatment for both manic and depressive symptoms. ECT is seldom used to treat bipolar I disorder, but can be helpful if medicines fail or can’t be used.

Can Bipolar I Disorder Be Prevented?

The causes of bipolar disorder are not well understood. It’s not known if bipolar I disorder can be prevented entirely.

It is possible to lower the risk of episodes of mania or depression once bipolar disorder has developed. Regular therapy sessions with a psychologist or social worker can help people to identify factors that can destabilize mood (such as poor medication adherence, sleep deprivation, drug or alcohol abuse, and poor stress management), leading to fewer hospitalizations and feeling better overall. Taking medicine on a regular basis can help to prevent future manic or depressive episodes.

How Is Bipolar I Different From Other Types of Bipolar Disorder?

People with bipolar I disorder experience full episodes of mania — the often severe abnormally elevated mood and behavior described above. These manic symptoms can lead to serious disruptions in life (for example, spending the family fortune, or having an unintended pregnancy).

In bipolar II disorder, the symptoms of elevated mood never reach full-blown mania. They often pass for extreme cheerfulness, even making someone a lot of fun to be around — the “life of the party.” Not so bad, you might think — except bipolar II disorder usually involves extensive and disabling periods of significant depression, which can often be harder to treat than if episodes of hypomania had never occurred.

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