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Abstract All psychiatric disorders have suffered from a dearth of truly novel pharmacological interventions. In bipolar disorder, lithium remains a mainstay of treatment, six decades since its effects were serendipitously discovered. The lack of progress reflects several factors, including ignorance … Continue reading →

Abstract From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is almost certainly the case that many somewhat similar, but subtly different, pathological conditions produce a disease state that we currently diagnose as bipolarity. This … Continue reading →

Abstract Bipolar disorder is prevalent, with high risks of disability, substance abuse and premature mortality. Treatment responses typically are incomplete, especially for depressive components, so that many cases can be considered “treatment resistant.” We reviewed reports on experimental treatments for … Continue reading →

Abstract Bipolar disorder is a common, complex genetic disorder, but the mode of transmission remains to be discovered. Many researchers assume that common genomic variants carry some risk for manifesting the disease. The research community has celebrated the first genome-wide … Continue reading →

Depression and bipolar disorder are virtually never diagnosed together in the same person at the same time. Both are serious mental disorders that have many treatment options available to a person diagnosed with one of them. However, the treatments between … Continue reading →

Mood Disorders These disorders, also called affective disorders, may involve: Feeling sad all the time Losing interest in important parts of life Fluctuating between extreme happiness and extreme sadness The most common mood disorders are: Depression Bipolar Disorder Seasonal Affective … Continue reading →

Many creative people past and present — including artists, musicians, actors, and writers — are said to have had bipolar disorder. Find out if bipolar creativity is fact or fiction. Creativity and mental disorders often go hand-in-hand in popular culture. … Continue reading →

For most people with bipolar disorder, strict adherence to medications is necessary to help keep episodes to a minimum. Don’t Miss This 10 Tips for Coping With Spousal Mood Swings How Faith Helps People With Bipolar Disorder Sign Up for … Continue reading →

Depression and bipolar disorder are virtually never diagnosed together in the same person at the same time. Both are serious mental disorders that have many treatment options available to a person diagnosed with one of them. However, the treatments between … Continue reading →

Get the most out of your visit to the doctor. Don’t Miss This A Star’s Story of Bipolar Caregiving How to Decide on Inpatient Treatment for Bipolar Sign Up for Our Emotional Health Newsletter Submit Enter Your Email We respect … Continue reading →